Demi Moore is back with "The Substance," which co-star Dennis Quaid calls her "incredible third act" at Cannes.

All Photos Credits- demimoore Insta

The film, directed by Coralie Fargeat, premiered to a 13-minute standing ovation, the longest at Cannes' 77th edition.

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"The Substance" is a body horror with a feminist twist about a product that transforms people into younger versions of themselves.

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Moore plays an older TV aerobics host replaced by her younger self, played by Margaret Qualley, after taking the transformative drug.

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Moore chose the script for its challenging themes and the opportunity for personal and professional growth.

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The film explores validation and belonging, and Moore felt a greater acceptance of herself through the process.

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Addressing age-related cancellation, Moore emphasized the importance of self-perception over external judgments.

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Director Fargeat highlighted the film's focus on societal views of women's bodies and internalized violence.

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Moore clarified the movie is "anti-jerk" rather than anti-men, addressing gender-based societal issues.

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Quaid, dedicating his performance to Ray Liotta, praised the film for tackling taboo subjects and predicted its lasting impact.

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Demi Moore Reflects on Self-Acceptance After 'The Substance' – A Cannes Comeback Story

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